..seriously though!
The history of alchemy in particular, but really the whole of esoteric wisdom, includes a belief that the earth is a macrocosmic equivalent of the human body...
this same idea provided the basis for the blueprints of the earliest cathedrals...see some information on the ideological background of Dionysius, the man credited with supplying the philosophico-religious foundation for the St. Denis cathedral, the first "gothic" cathedral built...
now, if Konami could dig up some of the particulars about how the micro-macrocosmic correlation between things such as a human body and a building were seen to work, I think it would be a small step, with the inclusion of some serious imagination (something Konami is in no shortage of), towards actualizing such an idea as this...
I'm thinking the gamer could be on the dark side, obviously, utilizing the castle's "limbs" and "psychology" so as to befuddle an AI vampire killer...what does everyone think?