Well, hopefully Anderson doesn't make it his own baby and thus killing the original source material like Resident Evil. Having beloved characters be secondary, expendable, wimpy characters just is a kick in the teeth for the true fans.
I'm sick and tired about hearing about Alice through three RE movies, while faves like Wesker, Claire and Jill are barely touched on, and Chris and Leon haven't even appeared yet. Seeing some nice nods in scenes in Apocalypse was nice, but when it's fucking Alice being the star sucks. But Extinction just kills it with Wesker merely being some idiot suit behind a desk and an army of Alice clones is just too much. You don't shit on the beloved characters that the fans love in the first place.
If, however, Anderson keeps it somewhat close like the first Mortal Kombat movie (one of my all-time favorite movies), I'll be happy.