Best: The music. i can't choose actual sequences, I like too many. But the music stands out most to me
Worst: Victor's death, hands down. In fact it's even worse than the ending to me. At least you can swallow the ending as "open ended" or try and make it make sense, but not Victor's death.
also FYI I liked the train sequence. I was like, WOOOOW, I loved that line by Dracula too- "Only I live forever!"