This is an interesting time for Castlevania. We have two games in front of us. LoS represents a change in direction, style, and an expansion of the fanbase. Possibly even a return to the popularity Castlevania has held in the past. Meanwhile HoD represents an embrace of everything that's come before. It brings very little innovation to the table, no real story that I can tell, and nothing new besides the ability to view the entire castle on one screen.
Harmony of Despair looks like it will be fun to play, but so does the Pachi Slot, the Arcade game, and the Puzzle fighter. There's nothing wrong with buying these games and enjoying them. But, at the end of the day, none of these games are going to keep the franchise going. Sure, they may expand it a little, but they aren't what will draw in new players and put Castlevania back in league with games like Mario and Metroid.
Ultimately, Konami is a company. Companies don't care about anything but profit, that's why they exist. LoS is the future of Castlevania as far as Konami is concerned. If it fails, we might as well say goodnight to the majority of the series for another decade, until Konami feels brave enough to try again. That's not something I want to happen. Some of you are still waiting for Iga to save the day, but it's pretty obvious he can't. I enjoy the games he makes. OoE was probably one of my favorites. But in general, the games he makes don't appeal to the mass market. This is why Konami keeps cutting his budget, and why they are looking for a new direction. Even if the future of CV isn't LoS, Iga is still the past.
Also, Harmony of Despair and LoS are not comparable games. So it's a waste of time to argue about it. Some people may like one over the other, which is fine, but they aren't comparable just because they share the Castlevania name. That would be like trying to compare billiards with water polo just because they are both consideres "sports".