Well, he said Simon would not be in LoS 2- that could just mean he isnt a boss or anything, but might could still be the one to seal Dracula in a cutscene.
otherwise, Richter seems a pretty safe bet for an inbetween Belmont, between eras. I mean, if they are bringing out heavyweights like Trevor and Simon, and possibly Julius if the rumors are true- then they might as well go all out and bring in the other fan favorite Belmont right? Especially since they really seem to want to do something with Alucard in both MoF and LoS2.
OR, Alucard could defeat him ala SoTN and be the one who then seals him...
Im really excited about LoS2 more than MoF because theres really little precedent for it. MoF leads into it, but MoF is really just another castlevania. LoS2 has you however, as the main antagonist, fighting off the brotherhood, then time skipping you to the present day, which is the REAL mystery here. What they will do with it.
I think it's a pretty safe bet that they will start you off in the past, as the all powerful annihilator of everything for a little while, maybe just a quick boss fight, And then take your candy away and seal you up and toss you into modern day all decrepit and without your powers... Which you slowly regain.