Man, I wish they'd given more than just this 2 minute trailer. We can only guess what this Other M will be like, and considering that trailers tend to only show the most intense sequences of action, the trailer can't be used as a complete guide to what the whole game will actually be like.
One interesting thing, though, was that blond lady in the lab coat near the end, more specifically the repressed surprise she seemed to have when Samus identified herself. Could she possibly be a clone? a Samus from another dimension or alternate timeline? a relative? maybe even an SA-X? or just some random woman who happens to look an awful lot like Samus?