Only CV Adventure and Bloodlines. CVA was a royal pain in the ass till I finally learned how to land jumps in the game (still suck at the game though). Sure it's ploddingly slow, but the music is ace, plus it is one of the first GB titles when the system came out, Konami may not have been familiar with the hardware yet, look at Belmont's Revenge to see it didn't take them long to learn.
Bloodlines, wellll I was a Nintendo kid growing up (after my Atari 2600 days of the late 70's to mid 80's), and I didn't care for Sega at that time. I laughed at screenshots in EGM and Gamepro at the time simply because I thought it and Contra Hard Corp didn't look all that hot. Things changed when my cousin brought me over to his house to beat the Tower of Pisa level, mind you I never touched the game before in my life till then. Not only did I clear the stage, I aced the Gargoyle without being hit, needless to say he was stunned I did something he couldn't do. Long story short in 1998 I bought my first Genesis, a model 2, and bought the Majesco re-releases of Bloodlines and Hard Corp. It was then I realized I was wrong all those years about Sega hardware (and being 23 at that time helped) and started enjoying both games. I felt Bloodlines was a return to an older style of CV, stuff we saw in CV1 and 3 with some changes and stuff brought over from SCV 4 (whip swinging). Some familiar enemies looked a little different, but I managed to recognize them (though the Bone Pillar Dragons sure looked the same, the bastards) and enjoy the game even more.