LoS has definitely the best storytelling and the most coherent plot (also helped by unprecedented, even if very uneven, exposition for the serie's standard); however this challenge risks to come off as some sort of paraolympic competition.
Don't misunderstand, I think the potential for CV's storyline has always been extremely strong; in fact, the entire idea of Dracula and a clan of vampire hunters going after him every 100 years in preparation for an apocalyptic confrontation at the eve of the millenium is just gold. Small problem is, that's the narrated premise to every game, which then ends up being a confused mess of dislodged dialogues that further such story one inch per console generation.
Let's hope LoS helps Konami flesh out the amazing potential here. I know some people hates Kojima; but just imagine a slightly less logorroic Kojima giving CV's story the MGS treatment. Recurring villains, machinations, overarching plots, and so on.
The actual potential for CV is absurd. You could have epic spanning plots involving Dracula's own misterious plans, Death serving him while working towards his own ends, ancient vampire rivals opposing both the Belmonts and Dracula, Corvinus of Hungary scheming against his old rival, the involvement of the Church, a group of holy templars secretly manipulated by a Nosferatu vampire who wants Dracula's power... you could fit in basically any idea. You just need to storytellers to grow out of the revenge megaplot, stop focusing on 2 characters at a time and build games that have an actual cast outside of the hero and the 3 npcs that help him along the way.