Here's some bits from an IGN interview.
IGN Wireless: How is it tied to other Castlevania storylines?
TR (Tyrone Rodriguez the game's lead designer): Castlevania: Order of Shadows' main protagonist is a Belmont. He's doing what Beltmonts do best.
IGN Wireless: How closely are you working with Koji Igarashi for this new title? Was he pretty hands on during the development, or did he just offer some guidance? Did he enjoy the challenge of working on a new platform, or was it outside his expertise?
TR: We met with IGA pretty early on in the development process, he gave his blessing, but also reminded us that the game had to be fun and keep with the spirit of the Castlevania series. This needs no interpretation and reaffirmed our believe that the game had to be designed to embrace the mobile platform. IGA took a look at the design, story and script, giving his input and comments as necessary. He was actively involved with ensuring the game was consistent with the current canon. His attention to detail and knowledge of the series is obviously unrivaled. It's really great to have a living, breathing encyclopedia, even if he's in Roppongi Hills most of the time.
IGA knows games, there's probably nothing related or unrelated to Castlevania he can't handle. His background is in programming so he understands the challenges of mobile. That's been a huge help—he even came up with a few solutions on how to improve hit detection and the whip mechanics.
IGN Wireless: What sort of timeframe in relation to other Castlevania titles?
TR: Officially, Order of Chaos is considered a "gaiden" or side story to the Castlevania canon. However, it takes place roughly in the late 1600s.