I won't really care for a CV: Vampire Killer Rebirth. Don't get me wrong, The Adventure Rebirth was done well, but I don't really see the point in doing it. The only kind of "Rebirth" I would like to see is a CV3 re-birth. However, when I say a re-birth, I mean a different version of the game. Same storyline, but with different game play. For example, CV3. If I were to create a re-birth of it, I would do the following:
1) Turn it into a 3D game
2) Keep the stage-by-stage format
3) Institute a "Stage Select" feature like in RoB so that you could go back and revisit stages to do things you haven't already done
4) Add in collectable items like in DXC, but have a checklist to keep track of what you have done
5) Abolish switching characters in the middle of a stage and instead create different modes (one for each of the heros unlockable by having Trevor met them)
6) Remix the music from the original CV3 and add other songs for the stages
I think that such a game is a "True Re-Birth" and would be a big hit. Of course, it would likely be for one of the newer consoles.