Klonoa 3 needs to be made ASAP. It's my (dare I say it?) favourite series of platformers. Ever.
Suikoden 6. The PSP game that was released in Japan earlier this year is proof enough that Konami doesn't care anymore. I have no idea if the game was good or bad, but it sure wasn't Suikoden 6. Plus, releasing it on a dead handheld, making it Japan exclusive probably means that the series is over.
Tomba!/Tombi! 3 - Explanation unnecessary. Of course, it will never happen though.
Shenmue 3. Yeah. Uhm.. Next!
Phantasy Star 5 - Well, I doubt this will ever happen. And if it ever were to happen, I'm sure it would be something along the lines of Phantasy Star Universe. I can definitely live without that.