Now that I think of it, where the "zombies" we were all seeing in the screens those things seen in the picture with the Butcher? Those don't look like zombies to me. They look more like those vampires from Blade II. Though, considering how one is riding the Butcher's back, and how insect-like the mandibles are(which was a point made in Blade II), I'm wondering if those could be LoS's version of the Flea Men. It could make sense.
But yeah, those new monsters(the nose ones) scare the crap out of me. They remind me of that ugly little gnome from Cat's Eye. Though, I can actually see them existing in a CV game, and at least to me, the look more "at place" than those goblins. The Butcher, IMO, looks CRAZY! He's a boss, right? I'm hoping for some cool intro scene where we might see him cutting up human bodies before Gabriel enters the room(almost like the scene of the Butcher in Diablo).