I'm with Gabby on this one. The brotherhood and whoever is "really" pulling their strings needs to go. And I'm sure that humanity isn't entirely composed of the brotherhood.
Looking at all this "fate" thing, I'm a bit of the opinion that God (or whatever higher being might be there instead) is more actively being a dick to "Dracula" in this continuity.
At least God in the IGAverse stopped at Drac's wife (or wives, if you count the wrongful execution of Lisa Fahrenheights Tepes that might be orchestrated by someone else (hey, Isaac was behind Rosaly's)), here He pretty much decided "oh hey let's make you kill your own son too while I'm at it." (I consider Trevor already dead by the time Gabe vampirizes him.)